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Ivermectin is an antiparasitic drug that is actively used in the treatment of humans, cattle, pigs, and artiodactyls. The drug is highly effective. It has been studied for a long time and has undergone numerous clinical trials that have proven its safety for humans.
Initially, Ivermectin was used only in the treatment of animals. In veterinary practice, the drug is actively used. This is one of the few drugs that effectively fight helminthiasis in large farm animals. It is available in different forms - tablets, injection solutions.
The antiparasitic effect of the drug is aimed at combating scabies mites, helminths, lice, i.e. with different groups of parasites. It is used to treat people and animals.
Ivermectin is used externally, orally and by injection. Under the influence of the drug, neuromuscular impulses are blocked. This provokes paralysis and death of the parasites.
Despite its broad spectrum of action, the drug has low toxicity. Compliance with the instructions for use and dosage rules rarely leads to side effects.
The drug is characterized by rapid absorption and uniform distribution in tissues. The highest concentration in the blood is reached after approximately 4 hours. The half-life in humans is 12-16 hours.
The drug effectively copes with infections caused by roundworms. In addition, with the help of this drug you can get rid of lice and various types of mites that parasitize humans. The medicine is indicated for:
The drug works well in treating itching in the anogenital area.
Before use, consult a doctor. For some diseases accompanied by weakened immunity, the use of Ivermectin is undesirable.
Instructions for use
For human treatment, it is recommended to use Ivermectin tablets.
The medicine should be taken in the morning on an empty stomach, without chewing the tablet. The average dosage is 12 mg for a person weighing approximately 70 kg. The exact dosage of the drug is determined by the doctor, taking into account the weight and degree of invasion. The doctor also determines how many pills will be needed.
There should be a gap of at least 7 days between doses.
When treating certain diseases, the doctor may prescribe two doses of Ivermectin at once - orally and as an injection. In this case, at least a week should pass before the next use of the drug. The medicine can also be used externally. The ointment is applied to the affected areas of the skin.
The drug cannot be used to treat newborns and children under 5 years of age and weighing less than 15 kg. For older children with sufficient weight, Ivermectin is prescribed at the rate of 150 mcg of the drug per 1 kg of body weight.
During pregnancy and lactation
The drug is contraindicated for pregnant women and nursing mothers. Particular attention should be paid when planning pregnancy, as side effects may persist for a month and may negatively affect the process of conception.
Ivermectin should not be used if:
- the patient’s body weight is less than 15 kg and age is less than 5 years;
- a woman is carrying a child or breastfeeding;
- the patient suffers from renal or liver failure;
- the patient has an individual intolerance to the components of the drug;
- the patient suffers from asthma or meningitis;
- the patient experiences a general decrease in immunity.
Undesirable side effects may occur two days after taking the drug and manifest themselves as:
- headache and dizziness;
- drowsy state;
- skin rashes and itching;
- muscle pain;
- enlarged lymph nodes.
It is believed that side effects may be caused not by the toxicity of Ivermectin, but by the massive death of parasites. In rare cases, other side effects may occur, which are more likely related to the disease itself rather than to the drug taken.
Hypersensitivity to the components of the drug is usually accompanied by an allergic reaction, and therefore it is recommended to take Ivermectin simultaneously with antihistamines.
Interaction with other drugs
Ivermectin increases the level of warfarin in the blood, so it should not be used simultaneously with warfarin and phenylamine.
Concomitant use with barbiturates, sedatives and hypnotic psychoactive substances is not recommended, since these drugs increase GABAergic activity.
To avoid side effects, this medicine should not be taken with certain antidepressants such as fluoxetine, fluvoxamine, venlafaxine.
The use of alcohol and ivermectin is incompatible, since the drug is metabolized in the liver, and when taken with alcohol it has the greatest load.
The liver receives a double blow and reacts with intoxication of the body:
- deterioration in general health;
- decreased concentration;
- drowsiness and dizziness;
- disturbances in brain function;
- loss of consciousness.
Ivermectin User Reviews
Date: April 17, 2023
Discuss with your doctor everything in details, before starting Ivermectin treatment. Once it is settled, the rest of treatment will go just fine. At least, that’s how it was for me during threadworms treatment.
Date: May 21, 2023
Slight dizziness and mild fever – that’s the only side effects I had during Ivermectin treatment. The rest of my treatment was quite smooth, and I am glad that I can finally forget about onchocerciasis.
Date: June 11, 2023
Don’t bother about side effects while taking Ivermectin because they will disappear soon. At least, that’s how it was for me 4 months ago, when I was undergoing infection treatment. This medicine works fine, and you can always consult with your doctor in case of any adverse side effects occur.
Date: Aug 03, 2023
I’m quite pleased with the way Ivermectin works because my onchocerciasis is getting less severe and affects my body less than before. I am also glad to find no serious side effects, which means I can continue taking this medicine until I fully recover.
Date: Sept 14, 2023
My uncle had threadworms and I had onchocerciasis last year. We were quite uncertain about the correct medication to address our deteriorating conditions. Luckily, our doctor has suggested Ivermectin, because soon enough we were able to come back to our normal lifestyle again.
Date: Oct 12, 2023
If I ever face another infection, then Ivermectin will be my medicine of choice, because it has helped me recently already. There were some side effects, but rather tolerable. Just make sure you discuss everything in details with your healthcare specialist before starting the treatment.
Date: Oct 30, 2023
I was quite concerned about any side effects because other medicines were causing quite severe adverse effects. That’s why I have started taking Ivermectin only after it was prescribed by my physician. It’s been 4 weeks now and I don’t see any deviations from my normal conditions. Let’s hope I recover soon completely.
Date: Nov 07, 2023
Don’t hesitate to check out Ivermectin, if you are looking for a remedy to treat your infection. Based on my experience, this medicine has shown quite an impressive performance and that’s the reason why I advise it to others too.
Date: Nov 19, 2023
If you manage to find Ivermectin online or in standard drugstores, just give it a try. Because this medicine has worked for me just well. There were slight side effects, and they did not last very long. I am about to finish my treatment and really glad about it.
Date: Dec 11, 2023
Prior to switching to Ivermectin I have tried several other medications, however they were not able to ease my onchocerciasis condition. To my surprise, this drug worked just fine, and I could finally enjoy my life, just like a normal person.
Date: Jan 12, 2024
Ivermectin seems to be working fine so far, as I’m on my 3rd week of treatment. Some dizziness and fever were bothering me at first, but now I can see that my conditions are getting better. Let’s hope, the infection will be gone soon.
Date: Jan 20, 2024
I’d advise Ivermectin to others, who suffer from onchocerciasis and other infections, because it was very effective during my recent treatment cycle. Besides that, I didn’t observe any adverse side effects, but still advise everyone to maintain close contact with healthcare specialist throughout the treatment.